Insulin-like growth factor 1 (IGF-1) is a hormone alike in structure to insulin and works with growth hormone to regenerate and reproduce cells. The pituitary gland in the human brain secretes growth hormone which stimulates the liver to produce IGF-1 and it consequently stimulates cell growth throughout the body, leads to growth and development, strengthens tissues and heals skin, bones, gut lining, etc., IGF-1 is core to the development and if it is absent in the body with the adequate level, the child might bear with short stature.
IGF-1 is well known by its brand name Increlex and the generic name Mecasermin. Recombinant Human IGF1 is a bioactive protein intended for use in cell culture applications. IGF1 binds its receptor, IGF1R, activates several signaling pathways. IGF1 has directly involved in differentiation, survival, growth, proliferation, apoptosis and regeneration. Its high purity minimizes the interference from other contaminants and proteins, high biological activity yields more results with less protein and it shows proven compatibility.
How does IGF-1 work?
IGF-1 is released in the liver and binds to the IGF receptors within the cells, which ultimately causes cell growth stimulation, i.e. both new tissue formation and existing tissue growth, and inhibits cell death. IGF-1 is a highly anabolic and anti-catabolic compound. It yields many positive results for athletes and bodybuilders such as increased nitrogen retention and protein synthesis because of its anabolic property. IGF-1 along with sufficient protein promotes the growth of new muscle cells, which increases the overall number of cells in the muscles. It shields brain neurons and promotes the growth of new motor neurons, makes it possible to quickly learn new skills during its use. Insulin-like growth factor1 plays a vital role is connective tissue production, improving collagen formation, helping in cartilage repair. Similarly, this protects the bone by enhancing bone production and repair.
IGF-1 sales sources
Insulin Growth Factor-1 is a strict prescription only drug. It is a tough task to get the drug/injection without a legal prescription. However, there are numbers of nutritional and sports venue sale IGF-1 without a prescription. Though IGF-1 supplements do not contain a pure form, still nutrient that helps the pituitary in its manufacture and growth hormone release. Depending on the ingredients and purity only the drug yields the best results. Deer Antler Velvet is a popular IGF-1 supplement available in the current market in the forms of spray, drops, pills, tablets, powder, extract. The user should be cautious to read the label ingredients always while purchasing the drug without a proper prescription. The product may contain a nutrition label with a variety of minerals and vitamins as well as IGF-1. You may notice that number of products marketed as an IGF-1 supplement with a very meager amount of that particular hormone.
IGF-1 side effects:
Hypoglycemia or a drop in the blood sugar is a noted short term side effect. Changes in the physical appearance, suppression of proteins break down, and Acromegaly (abnormal growth of the hands, feet and facial features) is the long term downside effects of IGF-1.
Therapeutical human use of recombinant human IGF-I has been applied to treat the Laron syndrome, improve glycemic control in diabetes, treat neurological disease such as amyotrophic lateral sclerosis, Alzheimer disease, and multiple sclerosis. Some people use IGF-1 for anti-aging purpose which is strictly not recommended.